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| カタログ番号 | HT323014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CIDEA Polyclonal Antibody (HT323014) is a rabbit polyclonal antibody detecting CIDEA in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CIDEA (Arg35-Lys104). | ||||||||
| ターゲット | Cell death activator CIDE-A, CIDEA, Cell death-inducing DFFA-like effector A | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O60543 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lipid transferase CIDEA is a ~24 kDa protein. Lipid transferase that promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. May also act as a CEBPB coactivator in epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. 1. Liu, K. et al. (2009) American journal of physiology. Endocrinology and metabolism 297, E1395-413. PMID: 19843876 2. Abreu-Vieira, G. et al. (2015) Nature communications 6, 7433. PMID: 26118629 | ||||||||
| 注意事項 | For research use only. |
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