

| Каталожный номер | HT323014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human CIDEA Polyclonal Antibody (HT323014) is a rabbit polyclonal antibody detecting CIDEA in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CIDEA (Arg35-Lys104). | ||||||||
| Цель | Cell death activator CIDE-A, CIDEA, Cell death-inducing DFFA-like effector A | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O60543 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Lipid transferase CIDEA is a ~24 kDa protein. Lipid transferase that promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. May also act as a CEBPB coactivator in epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. 1. Liu, K. et al. (2009) American journal of physiology. Endocrinology and metabolism 297, E1395-413. PMID: 19843876 2. Abreu-Vieira, G. et al. (2015) Nature communications 6, 7433. PMID: 26118629 | ||||||||
| Примечание | For research use only. |
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