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Anti-Human CLDN2 Recombinant Antibody (SAA1651) (HX983013)

Anti-Human CLDN2 Recombinant Antibody (SAA1651)
Anti-Human CLDN2 Recombinant Antibody (SAA1651)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHX983013
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA1651
Objetivo CLDN2, SP82, Claudin-2
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P57739
RRID Anti-Human CLDN2 Antibody (SAA1651) (abinScience Cat# HX983013, RRID:AB_3727412)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Claudin-2 (CLDN2) is a ~24 kDa protein. Forms paracellular channels: polymerizes in tight junction strands with cation- and water-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability. In intestinal epithelium, allows for sodium and water fluxes from the peritoneal side to the lumen of the intestine to regulate nutrient absorption and clear enteric pathogens as part of mucosal immune response. In kidney, allows passive sodium and calcium reabsorption across proximal tubules from the lumen back to the bloodstream. In the hepatobiliary tract, allows paracellular water and cation fluxes in the hepatic perivenous areas and biliary epithelium to generate bile flow and maintain osmotic gradients.

1. Rosenthal, R. et al. (2010) Journal of cell science 123, 1913-21. PMID: 20460438
2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380
Nota For research use only.
Imágenes
  • Anti-Human CLDN2 Recombinant Antibody (SAA1651)

    SDS-PAGE

    SDS-PAGE for Anti-Human CLDN2 Antibody (SAA1651)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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