

| Каталожный номер | HT305117 |
|---|---|
| Реактивность видов | Human |
| Применения | ELISA, FCM, WB |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG2a, kappa |
| ID клона | SAA0509 |
| Конъюгация | FITC |
| Цель | CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin-4, Clostridium perfringens enterotoxin receptor, CPETR1 |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Связанные продукты | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC |
| Номер доступа | O14493 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Фон | Claudin-4 (CLDN4) is a ~22 kDa protein. Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own. 1. Shashikanth, N. et al. (2022) Nature communications 13, 3780. PMID: 35773259 2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380 |
| Примечание | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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