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Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509) (HT305107)

Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509)
Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509)
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Aperçu
Numéro de catalogueHT305107
Reactivité des espècesHuman
ApplicationsELISA, FCM, WB
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de cloneSAA0509
Cible CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin 4, Clostridium perfringens enterotoxin receptor, CPETR1
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès O14493
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Claudin-4 (CLDN4) is a ~22 kDa protein. Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own.

1. Shashikanth, N. et al. (2022) Nature communications 13, 3780. PMID: 35773259
2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380
Note For research use only.
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  • Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509)

    SDS-PAGE

    SDS-PAGE for Anti-Human CLDN4/Claudin-4 Antibody (SAA0509)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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