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| カタログ番号 | HP960137 |
|---|---|
| 種反応性 | Human |
| アプリケーション | FCM |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2a, kappa |
| クローンID | SAA0110 |
| 抱合 | APC |
| ターゲット | CLAX, C-type lectin domain family 2 member D, Osteoclast inhibitory lectin, CLEC2D, Lectin-like transcript 1, Lectin-like NK cell receptor, OCIL, LLT-1, LLT1 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC |
| アクセッション番号 | Q9UHP7 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | C-type lectin domain family 2 member D (CLEC2D/OCIL) is a ~21 kDa protein. Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. 1. Rosen, DB. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7796-9. PMID: 16339513 2. Germain, C. et al. (2010) The Journal of biological chemistry 285, 36207-15. PMID: 20843815 3. Hu, YS. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 89-99. PMID: 14753741 4. Gange, CT. et al. (2004) The Journal of biological chemistry 279, 29043-9. PMID: 15123656 5. Mathew, PA. et al. (2004) Molecular immunology 40, 1157-63. PMID: 15104121 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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