

| Número de catálogo | HF796013 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | SAA1543 | ||||
| Objetivo | CLPTM1, Cleft lip and palate transmembrane protein 1 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | O96005 | ||||
| RRID | Anti-Human CLPTM1 Antibody (SAA1543) (abinScience Cat# HF796013, RRID:AB_3727304) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Putative lipid scramblase CLPTM1 is a ~76 kDa protein. Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate. Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one. 1. Liu, YS. et al. (2018) The Journal of cell biology 217, 585-599. PMID: 29255114 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human CLPTM1 Antibody (SAA1543)
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