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Anti-Human CLPTM1 Recombinant Antibody (SAA1543) (HF796013)

Anti-Human CLPTM1 Recombinant Antibody (SAA1543)
Anti-Human CLPTM1 Recombinant Antibody (SAA1543)
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Especificación:
  • 50ug
  • 100ug
  • 1mg
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Vista general
Número de catálogoHF796013
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA1543
Objetivo CLPTM1, Cleft lip and palate transmembrane protein 1
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso O96005
RRID Anti-Human CLPTM1 Antibody (SAA1543) (abinScience Cat# HF796013, RRID:AB_3727304)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Putative lipid scramblase CLPTM1 is a ~76 kDa protein. Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate. Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one.

1. Liu, YS. et al. (2018) The Journal of cell biology 217, 585-599. PMID: 29255114
Nota For research use only.
Imágenes
  • Anti-Human CLPTM1 Recombinant Antibody (SAA1543)

    SDS-PAGE

    SDS-PAGE for Anti-Human CLPTM1 Antibody (SAA1543)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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