Anti-Human CMTM6 Recombinant Nanobody (SAA2685) (HD496013)

Name: Anti-Human CMTM6 Recombinant Nanobody (SAA2685)
Brand: abinScience
SKU: HD496013
Price: 191 USD
Availability: InStock

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1mg

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Каталожный номер	HD496013
Описание	Anti-Human CMTM6 Nanobody (SAA2685) [SAA2685] (HD496013) is a alpaca monoclonal antibody detecting CMTM6 in ELISA. Suitable for Human.
Реактивность видов	Human
Применения	ELISA
Хозяинский вид	Alpaca
Клоональность	Monoclonal
Изотип	VHH-8His
ID клона	SAA2685
Цель	CKLF-like MARVEL transmembrane domain-containing protein 6, CKLFSF6, CMTM6, Chemokine-like factor superfamily member 6
Уровень эндотоксинов	<10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q9NX76
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	CKLF-like MARVEL transmembrane domain-containing protein 6 (CMTM6) is a ~20 kDa protein. Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
Примечание	For research use only

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Anti-Human CMTM6 Recombinant Nanobody (SAA2685).pdf

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