Anti-Human CNOT7 Polyclonal Antibody (HA970014)

Name: Anti-Human CNOT7 Polyclonal Antibody
Brand: abinScience
SKU: HA970014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HA970014

Описание

Anti-Human CNOT7 Polyclonal Antibody (HA970014) is a rabbit polyclonal antibody detecting CNOT7 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CNOT7 (Arg11-Ser285).

Цель

CNOT7, BTG1-binding factor 1, CAF-1, CAF1, Caf1a, CCR4-NOT transcription complex subunit 7, CCR4-associated factor 1

Очистка

Purified by antigen affinity column.

Номер доступа

Q9UIV1

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

CCR4-NOT transcription complex subunit 7 (CNOT7) is a ~32 kDa protein. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex also seems to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression.

1. Horiuchi, M. et al. (2009) The Journal of biological chemistry 284, 13244-55. PMID: 19276069

2. Cooke, A. et al. (2010) The Journal of biological chemistry 285, 28506-13. PMID: 20634287

3. Kim, TH. et al. (2019) Science (New York, N.Y.) 365, 825-829. PMID: 31439799

4. Aslam, A. et al. (2009) Molecular biology of the cell 20, 3840-50. PMID: 19605561

5. Piao, X. et al. (2010) Molecular and cellular biology 30, 1486-94. PMID: 20065043

6. Doidge, R. et al. (2012) PloS one 7, e51331. PMID: 23236473

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human CNOT7 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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