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Anti-Human CNP Polyclonal Antibody (HY072014)

Anti-Human CNP Polyclonal Antibody
Anti-Human CNP Polyclonal Antibody
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Vista general
Número de catálogoHY072014
Descripción
Anti-Human CNP Polyclonal Antibody (HY072014) is a rabbit polyclonal antibody detecting CNP in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CNP (Glu40-Gly396).
Objetivo CNPase, 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP
Purificación Purified by antigen affinity column.
Número de acceso P09543
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) is a ~47 kDa protein. Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions.

1. Logue, J. et al. (2023) PLoS pathogens 19, e1011870. PMID: 38117830
Nota For research use only.
Imágenes
  • Anti-Human CNP Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-CNP polyclonal antibody at 1μg/ml on various samples.
    Lane 1: HepG2 cell lysate
    Lane 2: U251 cell lysate
    Lane 3: Hela cell lysate
    Lane 4: Mouse brain lysate
    Lane 5: Mouse cerebellum lysate
    Lane 6: Rat brain lysate
    Lane 7: Rat cerebellum lysate

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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