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| カタログ番号 | HY072014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CNP Polyclonal Antibody (HY072014) is a rabbit polyclonal antibody detecting CNP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CNP (Glu40-Gly396). | ||||||||
| ターゲット | CNPase, 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P09543 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) is a ~47 kDa protein. Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions. 1. Logue, J. et al. (2023) PLoS pathogens 19, e1011870. PMID: 38117830 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-CNP polyclonal antibody at 1μg/ml on various samples.
Lane 1: HepG2 cell lysate
Lane 2: U251 cell lysate
Lane 3: Hela cell lysate
Lane 4: Mouse brain lysate
Lane 5: Mouse cerebellum lysate
Lane 6: Rat brain lysate
Lane 7: Rat cerebellum lysate
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