

| Каталожный номер | HY072014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human CNP Polyclonal Antibody (HY072014) is a rabbit polyclonal antibody detecting CNP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CNP (Glu40-Gly396). | ||||||||
| Цель | CNPase, 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P09543 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) is a ~47 kDa protein. Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions. 1. Logue, J. et al. (2023) PLoS pathogens 19, e1011870. PMID: 38117830 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-CNP polyclonal antibody at 1μg/ml on various samples.
Lane 1: HepG2 cell lysate
Lane 2: U251 cell lysate
Lane 3: Hela cell lysate
Lane 4: Mouse brain lysate
Lane 5: Mouse cerebellum lysate
Lane 6: Rat brain lysate
Lane 7: Rat cerebellum lysate
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