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| カタログ番号 | HF544014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human COQ9 (Ser95-Arg318). | ||||||||
| ターゲット | Ubiquinone biosynthesis protein COQ9, mitochondrial, C16orf49, COQ9 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O75208 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ubiquinone biosynthesis protein COQ9, mitochondrial is a ~35 kDa protein. Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to COQ7, therefore facilitating the COQ7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. 1. Lohman, DC. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, E4697-705. PMID: 25339443 2. Lohman, DC. et al. (2019) Molecular cell 73, 763-774.e10. PMID: 30661980 3. Nicoll, CR. et al. (2024) Nature catalysis 7, 148-160. PMID: 38425362 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-COQ9 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
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