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| カタログ番号 | HT160024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CPLX1 Polyclonal Antibody (HT160024) is a rabbit polyclonal antibody detecting CPLX1 in ELISA, IHC, WB. Suitable for Macaca fascicularis, Mus musculus, Narke japonica, Human, and Bovine.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CPLX1 (Met1-Lys134). | ||||||||
| ターゲット | CPLX1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O14810 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Complexin-1, Complexin I, CPX I, Synaphin-2, CPLX1 | ||||||||
| 背景 | Complexin-1 (CPLX1) is a ~15 kDa protein. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior. 1. Kümmel, D. et al. (2011) Nature structural & molecular biology 18, 927-33. PMID: 21785414 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-CPLX1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse cerebellum lysate
Lane 3: Rat brain lysate
Lane 4: Rat cerebellum lysate
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