

| Número de catálogo | HD657014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human CRAT Polyclonal Antibody (HD657014) is a rabbit polyclonal antibody detecting CRAT. Suitable for Human, Rat, and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CRAT (His31-Glu297). | ||||||||
| Objetivo | CAT, CAT1, CRAT, Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CrAT, EC:2.3.1.137, EC:2.3.1.7 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P43155 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Carnitine O-acetyltransferase (CRAT) is a ~70 kDa protein. Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates. 1. Govindasamy, L. et al. (2004) Journal of structural biology 146, 416-24. PMID: 15099582 2. Drecourt, A. et al. (2018) American journal of human genetics 102, 266-277. PMID: 29395073 3. Violante, S. et al. (2013) Biochimica et biophysica acta 1832, 773-9. PMID: 23485643 | ||||||||
| Nota | For research use only |

Lane 1: Rat heart lysate
Lane 2: Rat skeletal muscle lysate
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