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| カタログ番号 | HD657014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CRAT Polyclonal Antibody (HD657014) is a rabbit polyclonal antibody detecting CRAT. Suitable for Human, Rat, and Mouse.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CRAT (His31-Glu297). | ||||||||
| ターゲット | CAT, CAT1, CRAT, Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CrAT, EC:2.3.1.137, EC:2.3.1.7 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P43155 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Carnitine O-acetyltransferase (CRAT) is a ~70 kDa protein. Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates. 1. Govindasamy, L. et al. (2004) Journal of structural biology 146, 416-24. PMID: 15099582 2. Drecourt, A. et al. (2018) American journal of human genetics 102, 266-277. PMID: 29395073 3. Violante, S. et al. (2013) Biochimica et biophysica acta 1832, 773-9. PMID: 23485643 | ||||||||
| 注意事項 | For research use only |
Lane 1: Rat heart lysate
Lane 2: Rat skeletal muscle lysate
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