

| Número de catálogo | HV447014 | ||||||||
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| Descripción |
Anti-Human CRTC1 Polyclonal Antibody (HV447014) is a rabbit polyclonal antibody detecting CRTC1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CRTC1 (Lys9-Gly74). | ||||||||
| Objetivo | WAMTP1, Transducer of CREB protein 1, TORC1, KIAA0616, MECT1, CREB-regulated transcription coactivator 1, CRTC1, Mucoepidermoid carcinoma translocated protein 1, TORC-1, Transducer of regulated cAMP response element-binding protein 1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q6UUV9 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | CREB-regulated transcription coactivator 1 (CRTC1) is a ~67 kDa protein. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. | ||||||||
| Nota | For research use only. |
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