

| Numéro de catalogue | HV447014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human CRTC1 Polyclonal Antibody (HV447014) is a rabbit polyclonal antibody detecting CRTC1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CRTC1 (Lys9-Gly74). | ||||||||
| Cible | WAMTP1, Transducer of CREB protein 1, TORC1, KIAA0616, MECT1, CREB-regulated transcription coactivator 1, CRTC1, Mucoepidermoid carcinoma translocated protein 1, TORC-1, Transducer of regulated cAMP response element-binding protein 1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6UUV9 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
||||||||
| Informations d'utilisation du produit |
| ||||||||
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | CREB-regulated transcription coactivator 1 (CRTC1) is a ~67 kDa protein. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. | ||||||||
| Note | For research use only. |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
Accès rapide
Contactez-nous
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский