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Anti-Human M-CSF Recombinant Antibody (SAA0417) (HY515107)

Anti-Human M-CSF Recombinant Antibody (SAA0417)
Anti-Human M-CSF Recombinant Antibody (SAA0417)
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  • 概要

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  • 参考文献

  • データシート

  • SDS

概要
カタログ番号HY515107
種反応性Human
アプリケーションELISA, FCM
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG2a, kappa
クローンIDSAA0417
ターゲット CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P09603
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 0.09% Sodium azide.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Macrophage colony-stimulating factor 1 (CSF1/M-CSF) is a ~60 kDa protein. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.

参考文献 1. Jia S, et al. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2018;13(7):1844-1852. [HY515107]
注意事項 For research use only.
イメージ
  • Anti-Human M-CSF Recombinant Antibody (SAA0417)

    Bioactivity

    Detects CSF1/M-CSF in indirect ELISA.

参考文献
Formula
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