

| Numéro de catalogue | HV349437 |
|---|---|
| Reactivité des espèces | Human |
| Applications | FCM |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| ID de clone | IND-2 |
| Conjugaison | APC |
| Cible | Chondroitin sulfate proteoglycan 4, CSPG4, Chondroitin sulfate proteoglycan NG2, MCSP, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Produits associés | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| Numéro d'accès | Q6UVK1 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | Chondroitin sulfate proteoglycan 4 (CSPG4/HMW-MAA) is a ~250 kDa protein. Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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