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| カタログ番号 | HT012014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CTDSP2 Polyclonal Antibody (HT012014) is a rabbit polyclonal antibody detecting CTDSP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CTDSP2 (Thr95-Pro271). | ||||||||
| ターゲット | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, 3.1.3.16, Nuclear LIM interactor-interacting factor 2, NLI-interacting factor 2, Protein OS-4, Small C-terminal domain phosphatase 2, Small CTD phosphatase 2, SCP2, CTDSP2, NIF2, OS4, SCP2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O14595 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2) is a ~30 kDa protein. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. | ||||||||
| 注意事項 | For research use only. |
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