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| カタログ番号 | HP851014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CTPS2 Polyclonal Antibody (HP851014) is a rabbit polyclonal antibody detecting CTPS2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CTPS2 (Met1-Lys297). | ||||||||
| ターゲット | CTPS2, CTP synthetase 2, UTP--ammonia ligase 2, CTP synthase 2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9NRF8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | CTP synthase 2 (CTPS2) is a ~65 kDa protein. CTP synthase involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. 1. van Kuilenburg, AB. et al. (2000) Biochimica et biophysica acta 1492, 548-52. PMID: 10899599 2. Han, GS. et al. (2005) The Journal of biological chemistry 280, 38328-36. PMID: 16179339 3. Lynch, EM. et al. (2020) Nature structural & molecular biology 27, 42-48. PMID: 31873303 4. Lynch, EM. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34583994 | ||||||||
| 注意事項 | For research use only. |
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