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Anti-Human CTTN Polyclonal Antibody (HC329014)

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Vista general
Número de catálogoHC329014
Descripción
Anti-Human CTTN Polyclonal Antibody (HC329014) is a rabbit polyclonal antibody detecting CTTN in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CTTN (Met1-Asn491).
Objetivo Src substrate cortactin, Oncogene EMS1, CTTN, Amplaxin, EMS1
Purificación Purified by antigen affinity column.
Número de acceso Q14247
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Src substrate cortactin (CTTN) is a ~61 kDa protein. Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in focal adhesion assembly and turnover.

1. von Holleben, M. et al. (2011) The Journal of biological chemistry 286, 13489-501. PMID: 21296879
2. Dudek, SM. et al. (2010) Molecular biology of the cell 21, 4042-56. PMID: 20861316
3. Williams, MR. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 17412-7. PMID: 17959782
4. Herrmann, S. et al. (2012) The Journal of biological chemistry 287, 44151-63. PMID: 23144454
5. Hashimoto, S. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 7036-41. PMID: 16636290
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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