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| カタログ番号 | HC329014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CTTN Polyclonal Antibody (HC329014) is a rabbit polyclonal antibody detecting CTTN in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CTTN (Met1-Asn491). | ||||||||
| ターゲット | Src substrate cortactin, Oncogene EMS1, CTTN, Amplaxin, EMS1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q14247 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Src substrate cortactin (CTTN) is a ~61 kDa protein. Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in focal adhesion assembly and turnover. 1. von Holleben, M. et al. (2011) The Journal of biological chemistry 286, 13489-501. PMID: 21296879 2. Dudek, SM. et al. (2010) Molecular biology of the cell 21, 4042-56. PMID: 20861316 3. Williams, MR. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 17412-7. PMID: 17959782 4. Herrmann, S. et al. (2012) The Journal of biological chemistry 287, 44151-63. PMID: 23144454 5. Hashimoto, S. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 7036-41. PMID: 16636290 | ||||||||
| 注意事項 | For research use only. |
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