Anti-Human CYP4F22 Polyclonal Antibody (HD330014)

Name: Anti-Human CYP4F22 Polyclonal Antibody
Brand: abinScience
SKU: HD330014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HD330014

Description

Anti-Human CYP4F22 Polyclonal Antibody (HD330014) is a rabbit polyclonal antibody detecting CYP4F22. Suitable for Human.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CYP4F22 (Asn66-Ala531).

Cible

CYP4F22, Cytochrome P450 4F22, EC:1.14.14.177, Ultra-long-chain fatty acid omega-hydroxylase

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q6NT55

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Ultra-long-chain fatty acid omega-hydroxylase (CYP4F22) is a ~61 kDa protein. A cytochrome P450 monooxygenase involved in epidermal ceramide biosynthesis. Hydroxylates the terminal carbon (omega-hydroxylation) of ultra-long-chain fatty acyls (C28-C36) prior to ceramide synthesis. Contributes to the synthesis of three classes of omega-hydroxy-ultra-long chain fatty acylceramides having sphingosine, 6-hydroxysphingosine and phytosphingosine bases, all major lipid components that underlie the permeability barrier of the stratum corneum. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).

1. Ohno, Y. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 7707-12. PMID: 26056268

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human CYP4F22 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human CYP4F22 Polyclonal Antibody (HD330014)

Aperçu

Images

Reférences

Fiche technique

SDS