

| カタログ番号 | HV254014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human D2HGDH Polyclonal Antibody (HV254014) is a rabbit polyclonal antibody detecting D2HGDH in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, and Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human D2HGDH (Arg56-Asp232). | ||||||||
| ターゲット | D2HGDH | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8N465 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | D-2-hydroxyglutarate dehydrogenase, mitochondrial, 1.1.99.39, D2HGDH, D2HGD | ||||||||
| 背景 | D-2-hydroxyglutarate dehydrogenase, mitochondrial (D2HGDH) is a ~56 kDa protein. Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate. Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC. 1. Achouri, Y. et al. (2004) The Biochemical journal 381, 35-42. PMID: 15070399 2. Struys, EA. et al. (2005) American journal of human genetics 76, 358-60. PMID: 15609246 3. Struys, EA. et al. (2005) Annals of neurology 58, 626-30. PMID: 16037974 4. Kranendijk, M. et al. (2010) Human mutation 31, 279-83. PMID: 20020533 5. Yang, J. et al. (2021) Cell discovery 7, 3. PMID: 33431826 | ||||||||
| 注意事項 | For research use only. |

Western blot analysis was performed using anti-D2HGDH polyclonal antibody at 1ug/mL on various samples.
Lane 1: NIH3T3 cell lysate


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