

| Numéro de catalogue | HV163014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human DBR1 Polyclonal Antibody (HV163014) is a rabbit polyclonal antibody detecting DBR1. Suitable for Human and Mouse.
Highlights
|
||||||||
| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human DBR1 (Met1-Pro273). | ||||||||
| Cible | DBR1, EC:3.1.4.-, Lariat debranching enzyme | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9UK59 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
||||||||
| Informations d'utilisation du produit |
| ||||||||
| Contexte | Lariat debranching enzyme (DBR1) is a ~61 kDa protein. Cleaves the 2'-5' phosphodiester linkage at the branch point of excised lariat intron RNA and converts them into linear molecules that can be subsequently degraded, thereby facilitating ribonucleotide turnover. Linked to its role in pre-mRNA processing mechanism, may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis and have an antiviral cell-intrinsic defense function in the brainstem. 1. Kim, JW. et al. (2000) Nucleic acids research 28, 3666-73. PMID: 10982890 2. Ye, Y. et al. (2005) Retrovirology 2, 63. PMID: 16232320 3. Arenas, J. et al. (1987) The Journal of biological chemistry 262, 4274-9. PMID: 2435736 4. Zhang, SY. et al. (2018) Cell 172, 952-965.e18. PMID: 29474921 | ||||||||
| Note | For research use only |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
Accès rapide
Contactez-nous
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский