

| Número de catálogo | HB117014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human DCK Polyclonal Antibody (HB117014) is a rabbit polyclonal antibody detecting dCK in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human DCK (Met1-Leu260). | ||||||||
| Objetivo | dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P27707 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Deoxycytidine kinase (DCK) is a ~30 kDa protein. Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. 1. Sabini, E. et al. (2003) Nature structural biology 10, 513-9. PMID: 12808445 2. Sabini, E. et al. (2008) Journal of molecular biology 378, 607-21. PMID: 18377927 3. Hazra, S. et al. (2009) Biochemistry 48, 1256-63. PMID: 19159229 4. Chottiner, EG. et al. (1991) Proceedings of the National Academy of Sciences of the United States of America 88, 1531-5. PMID: 1996353 5. Hazra, S. et al. (2010) Biochemistry 49, 6784-90. PMID: 20614893 6. Smal, C. et al. (2010) Archives of biochemistry and biophysics 502, 44-52. PMID: 20637175 | ||||||||
| Nota | For research use only. |
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