

| Каталожный номер | HB117014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human DCK Polyclonal Antibody (HB117014) is a rabbit polyclonal antibody detecting dCK in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human DCK (Met1-Leu260). | ||||||||
| Цель | dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P27707 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Deoxycytidine kinase (DCK) is a ~30 kDa protein. Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. 1. Sabini, E. et al. (2003) Nature structural biology 10, 513-9. PMID: 12808445 2. Sabini, E. et al. (2008) Journal of molecular biology 378, 607-21. PMID: 18377927 3. Hazra, S. et al. (2009) Biochemistry 48, 1256-63. PMID: 19159229 4. Chottiner, EG. et al. (1991) Proceedings of the National Academy of Sciences of the United States of America 88, 1531-5. PMID: 1996353 5. Hazra, S. et al. (2010) Biochemistry 49, 6784-90. PMID: 20614893 6. Smal, C. et al. (2010) Archives of biochemistry and biophysics 502, 44-52. PMID: 20637175 | ||||||||
| Примечание | For research use only. |
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