

| Numéro de catalogue | HF803014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human DDHD2 Polyclonal Antibody (HF803014) is a rabbit polyclonal antibody detecting DDHD2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
|
||||||||
| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human DDHD2 (Gln212-Asn363). | ||||||||
| Cible | KIAA0725, DDHD domain-containing protein 2, DDHD2, Phospholipase DDHD2, KIAA0725p, SAMWD1, SAM, WWE and DDHD domain-containing protein 1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O94830 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
||||||||
| Informations d'utilisation du produit |
| ||||||||
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Triacylglycerol hydrolase DDHD2 is a ~81 kDa protein. Diacylglycerol (DAG) and triacylglycerol (TAG) lipase required for proper lipid homeostasis in the central nervous system. It cooperates with PNPLA2/ATGL in neuronal TAG catabolism and hydrolyzes sn-1,3 DAG downstream of PNPLA2/ATGL. In vitro, it also acts as a phospholipase that hydrolyzes preferentially phosphatidic acids, including 1,2-dioleoyl-sn-phosphatidic acid, phosphatidylcholine and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. 1. Inloes, JM. et al. (2018) Biochemistry 57, 827-838. PMID: 29278326 2. Hofer, P. et al. (2023) Journal of lipid research 64, 100457. PMID: 37832604 | ||||||||
| Note | For research use only. |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
Accès rapide
Contactez-nous
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский