Anti-Human DDX3X Polyclonal Antibody (HT313014)

Name: Anti-Human DDX3X Polyclonal Antibody
Brand: abinScience
SKU: HT313014
Price: 96 USD
Availability: InStock

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Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HT313014

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human DDX3X (Glu161-Ser410).

Objetivo

DEAD box, X isoform, CAP-Rf, DDX3, HLP2, DEAD box protein 3, X-chromosomal, DDX3X, ATP-dependent RNA helicase DDX3X, Helicase-like protein 2, DBX

Purificación

Purified by antigen affinity column.

Número de acceso

O00571

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

ATP-dependent RNA helicase DDX3X is a ~73 kDa protein. Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo-and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'-single-stranded DNA overhangs. Binds RNA G-quadruplex (rG4s) structures, including those located in the 5'-UTR of NRAS mRNA. Involved in many cellular processes, which do not necessarily require its ATPase/helicase catalytic activities (Probable).

1. Franca, R. et al. (2007) Proteins 67, 1128-37. PMID: 17357160

2. Garbelli, A. et al. (2011) PloS one 6, e19810. PMID: 21589879

3. Heaton, SM. et al. (2019) Cells 8. PMID: 31575075

4. Dolde, C. et al. (2018) Journal of cell science 131. PMID: 29222110

5. Herdy, B. et al. (2018) Nucleic acids research 46, 11592-11604. PMID: 30256975

6. Chao, CH. et al. (2006) Cancer research 66, 6579-88. PMID: 16818630

7. Botlagunta, M. et al. (2008) Oncogene 27, 3912-22. PMID: 18264132

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human DDX3X Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo