Anti-Human DDX46 Polyclonal Antibody (HD537014)

Name: Anti-Human DDX46 Polyclonal Antibody
Brand: abinScience
SKU: HD537014
Price: 168 USD
Availability: InStock

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50ug
100ug

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HD537014

Description

Anti-Human DDX46 Polyclonal Antibody (HD537014) is a rabbit polyclonal antibody detecting DDX46. Suitable for Rat, Human, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human DDX46 (Asp322-Lys765).

Cible

DDX46, DEAD box protein 46, EC:3.6.4.13, KIAA0801, PRP5 homolog, Probable ATP-dependent RNA helicase DDX46

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q7L014

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Probable ATP-dependent RNA helicase DDX46 is a ~117 kDa protein. Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, DDX46 plays essential roles during assembly of pre-spliceosome and proofreading of the branch site.

1. Will, CL. et al. (2002) The EMBO journal 21, 4978-88. PMID: 12234937

2. Zhang, Z. et al. (2020) Nature 583, 310-313. PMID: 32494006

3. Tholen, J. et al. (2022) Science (New York, N.Y.) 375, 50-57. PMID: 34822310

4. Yang, F. et al. (2023) Nature communications 14, 897. PMID: 36797247

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human DDX46 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human DDX46 Polyclonal Antibody (HD537014)

Aperçu

Images

Reférences

Fiche technique

SDS