

| Número de catálogo | HA418014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human DDX5 Polyclonal Antibody (HA418014) is a rabbit polyclonal antibody detecting DDX5. Suitable for Mouse and Human.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human DDX5 (Arg68-Ser483). | ||||||||
| Objetivo | DDX5, DEAD box protein 5, EC:3.6.4.13, G17P1, HELR, HLR1, Probable ATP-dependent RNA helicase DDX5, RNA helicase p68 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P17844 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Probable ATP-dependent RNA helicase DDX5 is a ~69 kDa protein. Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. | ||||||||
| Nota | For research use only |

Western blot analysis was performed using anti-DDX5 polyclonal antibody at 1ug/mL on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: 4T1 cell lysate
Lane 3: RAW264.7 cell lysate
Lane 4: Mouse brain lysate
Lane 5: Rat brain lysate
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