Anti-Human DEFA5 Polyclonal Antibody (HX187014)

Name: Anti-Human DEFA5 Polyclonal Antibody
Brand: abinScience
SKU: HX187014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HX187014

説明

Anti-Human DEFA5 Polyclonal Antibody (HX187014) is a rabbit polyclonal antibody detecting DEFA5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

種反応性

Human

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human DEFA5 (Glu20-Arg94).

ターゲット

HD5(20-94), DEF5, Defensin-5, DEFA5, Defensin, alpha 5

精製

Purified by antigen affinity column.

アクセッション番号

Q01523

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Defensin alpha 5 (DEFA5) is a ~10 kDa protein. Host-defense peptide that maintains sterility in the urogenital system. Has antimicrobial activity against a wide range of bacteria, including Gram-negative E.coli, P.aeruginosa and S.typhimurium, and Gram-positive E.aerogenes, S.aureus, B.cereus, E.faecium and L.monocytogenes. Confers resistance to intestinal infection by S.typhimurium. Exhibits antimicrobial activity against enteric commensal bacteria such as B.adolescentis, L.acidophilus, B.breve, L.fermentum, B.longum and S.thermophilus. Binds to bacterial membranes and causes membrane disintegration.

1. Ghosh, D. et al. (2002) Nature immunology 3, 583-90. PMID: 12021776

2. Salzman, NH. et al. (2003) Nature 422, 522-6. PMID: 12660734

3. Ericksen, B. et al. (2005) Antimicrobial agents and chemotherapy 49, 269-75. PMID: 15616305

4. de Leeuw, E. et al. (2009) FEBS letters 583, 2507-12. PMID: 19589339

5. Spencer, JD. et al. (2012) PloS one 7, e31712. PMID: 22359618

6. Rajabi, M. et al. (2012) The Journal of biological chemistry 287, 21615-27. PMID: 22573326

7. Schroeder, BO. et al. (2015) Mucosal immunology 8, 661-71. PMID: 25354318

8. Wang, C. et al. (2015) Journal of medicinal chemistry 58, 3083-93. PMID: 25782105

9. Ehmann, D. et al. (2019) Proceedings of the National Academy of Sciences of the United States of America 116, 3746-3751. PMID: 30808760

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human DEFA5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human DEFA5 Polyclonal Antibody (HX187014)

概要

イメージ

参考文献

データシート

SDS