

| Número de catálogo | HX066014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human DEFB1 Polyclonal Antibody (HX066014) is a rabbit polyclonal antibody detecting DEFB1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human DEFB1 (Gly22-Lys68). | ||||||||
| Objetivo | Beta-defensin 1, BD-1, hBD-1, Defensin, beta 1, DEFB1, BD1, HBD1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P60022 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Beta-defensin 1 (DEFB1) is a ~7 kDa protein. Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. 1. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 | ||||||||
| Nota | For research use only. |
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