Please ensure Javascript is enabled for purposes of website accessibility
Inicio > Productos > Anticuerpos > Anticuerpos Primarios

Anti-Human DEFB4A Polyclonal Antibody (HT380014)

Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
Contáctenos
  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHT380014
Descripción
Anti-Human DEFB4A Polyclonal Antibody (HT380014) is a rabbit polyclonal antibody detecting DEFB4A. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human DEFB4A (Gly24-Pro64).
Objetivo BD-2, Beta-defensin 2, DEFB102, DEFB2, DEFB4, DEFB4A, Defensin beta 4A, Defensin, beta 2, SAP1, Skin-antimicrobial peptide 1, hBD-2
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso O15263
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Defensin beta 4A (DEFB4A) is a ~7 kDa protein. Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria. Antimicrobial activity against P.aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM. Also exhibits antimicrobial activity against the yeast C.albicans. Permeabilizes C.albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death. Acts as a ligand for C-C chemokine receptor CCR6.

1. Harder, J. et al. (2000) American journal of respiratory cell and molecular biology 22, 714-21. PMID: 10837369
2. Harder, J. et al. (1997) Nature 387, 861. PMID: 9202117
3. Järvå, M. et al. (2018) Science advances 4, eaat0979. PMID: 30050988
4. Yang, D. et al. (1999) Science (New York, N.Y.) 286, 525-8. PMID: 10521347
5. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036
Nota For research use only
Imágenes
Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recomendación

Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.

Correo: [email protected]

Lista de distribuidores