Anti-Human DEFB4A Polyclonal Antibody (HT380014)

Name: Anti-Human DEFB4A Polyclonal Antibody
Brand: abinScience
SKU: HT380014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HT380014

Description

Anti-Human DEFB4A Polyclonal Antibody (HT380014) is a rabbit polyclonal antibody detecting DEFB4A. Suitable for Human.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human DEFB4A (Gly24-Pro64).

Cible

BD-2, Beta-defensin 2, DEFB102, DEFB2, DEFB4, DEFB4A, Defensin beta 4A, Defensin, beta 2, SAP1, Skin-antimicrobial peptide 1, hBD-2

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O15263

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Defensin beta 4A (DEFB4A) is a ~7 kDa protein. Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria. Antimicrobial activity against P.aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM. Also exhibits antimicrobial activity against the yeast C.albicans. Permeabilizes C.albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death. Acts as a ligand for C-C chemokine receptor CCR6.

1. Harder, J. et al. (2000) American journal of respiratory cell and molecular biology 22, 714-21. PMID: 10837369

2. Harder, J. et al. (1997) Nature 387, 861. PMID: 9202117

3. Järvå, M. et al. (2018) Science advances 4, eaat0979. PMID: 30050988

4. Yang, D. et al. (1999) Science (New York, N.Y.) 286, 525-8. PMID: 10521347

5. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human DEFB4A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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