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| カタログ番号 | HA078013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1871 | ||||
| ターゲット | DENN domain-containing protein 1A, Connecdenn, FAM31A, Protein FAM31A, KIAA1608, DENND1A, Connecdenn 1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q8TEH3 | ||||
| RRID | Anti-Human DENND1A Antibody (SAA1871) (abinScience Cat# HA078013, RRID:AB_3727634) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | DENN domain-containing protein 1A (DENND1A) is a ~110 kDa protein. Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes. Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P. 1. Marat, AL. et al. (2010) The Journal of biological chemistry 285, 10627-37. PMID: 20154091 2. Yoshimura, S. et al. (2010) The Journal of cell biology 191, 367-81. PMID: 20937701 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human DENND1A Antibody (SAA1871)
+86-027-65523339
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