Anti-Human DEPTOR Polyclonal Antibody (HP016014)

Name: Anti-Human DEPTOR Polyclonal Antibody
Brand: abinScience
SKU: HP016014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
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Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HP016014

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human DEPTOR (Ser316-Cys409).

Objetivo

DEPDC6, DEP domain-containing protein 6, DEP domain-containing mTOR-interacting protein, DEPTOR

Purificación

Purified by antigen affinity column.

Número de acceso

Q8TB45

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

DEP domain-containing mTOR-interacting protein (DEPTOR) is a ~46 kDa protein. Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity.

1. Peterson, TR. et al. (2009) Cell 137, 873-86. PMID: 19446321

2. Gao, D. et al. (2011) Molecular cell 44, 290-303. PMID: 22017875

3. Zhao, Y. et al. (2011) Molecular cell 44, 304-16. PMID: 22017876

4. Duan, S. et al. (2011) Molecular cell 44, 317-24. PMID: 22017877

5. Yoon, MS. et al. (2015) Molecular cell 58, 549-56. PMID: 25936805

6. Zhao, L. et al. (2018) The Journal of biological chemistry 293, 4883-4892. PMID: 29382726

7. Wälchli, M. et al. (2021) eLife 10. PMID: 34519268

8. Heimhalt, M. et al. (2021) eLife 10. PMID: 34519269

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human DEPTOR Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo