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Anti-Human DESI2 Polyclonal Antibody (HC211014)

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Aperçu
Numéro de catalogueHC211014
Description
Anti-Human DESI2 Polyclonal Antibody (HC211014) is a rabbit polyclonal antibody detecting DESI2. Suitable for Mouse, Human, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human DESI2 (Met1-Leu194).
Cible C1orf121, DESI2, DeSI-2, Desumoylating isopeptidase 2, Deubiquitinase DESI2, EC:3.1.2.22, EC:3.4.19.12, FAM152A, PPPDE peptidase domain-containing protein 1, PPPDE1, Palmitoyl protein thioesterase DESI2, Protein FAM152A, S-depalmitoylase DESI2
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q9BSY9
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

Deubiquitinase DESI2 is a ~21 kDa protein. Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5).

1. Xie, X. et al. (2017) Biochemical and biophysical research communications 488, 291-296. PMID: 28483520
2. Luebben, AV. et al. (2022) Science advances 8, eabj8633. PMID: 35427157
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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