Anti-Human DHH Polyclonal Antibody (HT127014)

Name: Anti-Human DHH Polyclonal Antibody
Brand: abinScience
SKU: HT127014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HT127014

Description

Anti-Human DHH Polyclonal Antibody (HT127014) is a rabbit polyclonal antibody detecting DHH-N. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human DHH (Gly202-Gly396).

Cible

DHH, DHH-N, Desert hedgehog protein, Desert hedgehog protein N-product, EC:3.1.-.-, HHG-3

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O43323

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Desert hedgehog protein (DHH) is a ~43 kDa protein. The C-terminal part of the desert hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (N-product and C-product) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product (DHH-N). Both activities occur in the endoplasmic reticulum. Once cleaved, the C-product is degraded in the endoplasmic reticulum. Functions in cell-cell mediated juxtacrine signaling.

1. Pettigrew, CA. et al. (2014) Mechanisms of development 131, 137-49. PMID: 24342078

2. Hollier, PL. et al. (2021) Cardiovascular research 117, 2489-2501. PMID: 33063110

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human DHH Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human DHH Polyclonal Antibody (HT127014)

Aperçu

Images

Reférences

Fiche technique

SDS