Anti-Human DIO2 Polyclonal Antibody (HP806014)

Name: Anti-Human DIO2 Polyclonal Antibody
Brand: abinScience
SKU: HP806014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HP806014

説明

Anti-Human DIO2 Polyclonal Antibody (HP806014) is a rabbit polyclonal antibody detecting DIO2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human DIO2 (Leu69-Leu269).

ターゲット

DIO2, TXDI2, ITDI2, Type II iodothyronine deiodinase, Type-II 5'-deiodinase, Type 2 DI, 5DII, DIOII

精製

Purified by antigen affinity column.

アクセッション番号

Q92813

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Type II iodothyronine deiodinase (DIO2) is a ~30 kDa protein. Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination. Catalyzes the deiodination of L-thyroxine (T4) to 3,5,3'-triiodothyronine (T3), 3,3',5'-triiodothyronine (rT3) to 3,3'-diiodothyronine (3,3'-T2) and 3',5'-diiodothyronine (3',5'-T2) to 3'-monoiodothyronine (3'-T1) via outer-ring deiodination (ORD). Catalyzes the phenolic ring deiodinations of 3,3',5'-triiodothyronamine and 3',5'- diiodothyronamine.

1. Curcio-Morelli, C. et al. (2003) Endocrinology 144, 937-46. PMID: 12586771

2. Buettner, C. et al. (2000) Endocrinology 141, 4606-12. PMID: 11108274

3. Salvatore, D. et al. (1999) Biochimie 81, 535-8. PMID: 10403186

4. Piehl, S. et al. (2008) Rapid communications in mass spectrometry : RCM 22, 3286-96. PMID: 18821722

5. Piehl, S. et al. (2008) Endocrinology 149, 3037-45. PMID: 18339710

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human DIO2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human DIO2 Polyclonal Antibody (HP806014)

概要

イメージ

参考文献

データシート

SDS