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Anti-Human Dkk-1 Recombinant Antibody (SAA2072) (HF914023)

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Anti-Human Dkk-1 Recombinant Antibody (SAA2072)
Anti-Human Dkk-1 Recombinant Antibody (SAA2072)
Anti-Human Dkk-1 Recombinant Antibody (SAA2072)
Anti-Human Dkk-1 Recombinant Antibody (SAA2072)
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Especificación:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
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Vista general
Número de catálogoHF914023
Reactividad de especiesHuman
AplicacionesELISA, Neutralization
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonSAA2072
Objetivo Dickkopf-1, SK, hDkk-1, Dkk-1, Dickkopf-related protein 1, DKK1
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso O94907
RRID Anti-Human DKK1 Antibody (SAA2072) (abinScience Cat# HF914023, RRID:AB_3729296)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Dickkopf-related protein 1 (DKK1) is a ~28 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.

1. Ahn, VE. et al. (2011) Developmental cell 21, 862-73. PMID: 22000856
2. Niehrs, C. (2006) Oncogene 25, 7469-81. PMID: 17143291
Nota For research use only.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Imágenes
  • Anti-Human Dkk-1 Recombinant Antibody (SAA2072)

    Bioactivity

    Detects Human DKK1 in indirect ELISAs.

  • Anti-Human Dkk-1 Recombinant Antibody (SAA2072)

    SDS-PAGE

    SDS-PAGE for Anti-Human DKK1 Antibody (SAA2072).

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human Dkk-1 Recombinant Antibody (SAA2072)

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