Anti-Human DNAJB2 Polyclonal Antibody (HB700014)

Name: Anti-Human DNAJB2 Polyclonal Antibody
Brand: abinScience
SKU: HB700014
Price: 96 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD): --

Especificación:

20ug
50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB700014

Descripción

Anti-Human DNAJB2 Polyclonal Antibody (HB700014) is a rabbit polyclonal antibody detecting DNAJB2 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human DNAJB2 (Ala2-Gly91).

Objetivo

HSJ-1, Heat shock protein J1, DNAJB2, Heat shock 40 kDa protein 3, DnaJ homolog subfamily B member 2, HSPF3, HSJ1

Purificación

Purified by antigen affinity column.

Número de acceso

P25686

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

DnaJ homolog subfamily B member 2 (DNAJB2) is a ~35 kDa protein. Functions as a co-chaperone, regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family. In parallel, also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins. Thereby, may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT, MC4R, PRKN, RHO and SOD1 and be crucial for many biological processes. Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins.

1. Gao, XC. et al. (2012) The Journal of biological chemistry 287, 6044-52. PMID: 22219199

2. Cheetham, ME. et al. (1994) European journal of biochemistry 226, 99-107. PMID: 7957263

3. Westhoff, B. et al. (2005) Current biology : CB 15, 1058-64. PMID: 15936278

4. Gao, XC. et al. (2011) PloS one 6, e19763. PMID: 21625540

5. Chapple, JP. et al. (2003) The Journal of biological chemistry 278, 19087-94. PMID: 12754272

6. Rose, JM. et al. (2011) Human molecular genetics 20, 16-27. PMID: 20889486

7. Meimaridou, E. et al. (2011) Molecular endocrinology (Baltimore, Md.) 25, 1650-60. PMID: 21719532

8. Labbadia, J. et al. (2012) Brain : a journal of neurology 135, 1180-96. PMID: 22396390

9. Novoselov, SS. et al. (2013) PloS one 8, e73944. PMID: 24023695

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human DNAJB2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human DNAJB2 Polyclonal Antibody (HB700014)

Vista general

Imágenes

Referencias

Datasheet

SDS