Anti-Human DNAJB6 Polyclonal Antibody (HF866014)

Name: Anti-Human DNAJB6 Polyclonal Antibody
Brand: abinScience
SKU: HF866014
Price: 96 USD
Availability: InStock

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Especificación:

20ug
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Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF866014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human DNAJB6 (Met1-Gly124).

Objetivo

HHDJ1, Heat shock protein J2, MRJ, HSJ-2, HSJ2, MSJ-1, DnaJ homolog subfamily B member 6, DNAJB6, MSJ1

Purificación

Purified by antigen affinity column.

Número de acceso

O75190

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

DnaJ homolog subfamily B member 6 (DNAJB6) is a ~36 kDa protein. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity.

1. Izawa, I. et al. (2000) The Journal of biological chemistry 275, 34521-7. PMID: 10954706

2. Tsai, PC. et al. (2017) Clinical genetics 92, 150-157. PMID: 28233300

3. Chuang, JZ. et al. (2002) The Journal of biological chemistry 277, 19831-8. PMID: 11896048

4. Sarparanta, J. et al. (2012) Nature genetics 44, 450-5, S1-2. PMID: 22366786

5. Hageman, J. et al. (2010) Molecular cell 37, 355-69. PMID: 20159555

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-DNAJB6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate

Referencias

Datasheet

Anti-Human DNAJB6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo