Anti-Human DNAJB6 Polyclonal Antibody (HF866014)

Name: Anti-Human DNAJB6 Polyclonal Antibody
Brand: abinScience
SKU: HF866014
Price: 96 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF866014

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human DNAJB6 (Met1-Gly124).

Cible

HHDJ1, Heat shock protein J2, MRJ, HSJ-2, HSJ2, MSJ-1, DnaJ homolog subfamily B member 6, DNAJB6, MSJ1

Purification

Purified by antigen affinity column.

Numéro d'accès

O75190

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

DnaJ homolog subfamily B member 6 (DNAJB6) is a ~36 kDa protein. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity.

1. Izawa, I. et al. (2000) The Journal of biological chemistry 275, 34521-7. PMID: 10954706

2. Tsai, PC. et al. (2017) Clinical genetics 92, 150-157. PMID: 28233300

3. Chuang, JZ. et al. (2002) The Journal of biological chemistry 277, 19831-8. PMID: 11896048

4. Sarparanta, J. et al. (2012) Nature genetics 44, 450-5, S1-2. PMID: 22366786

5. Hageman, J. et al. (2010) Molecular cell 37, 355-69. PMID: 20159555

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-DNAJB6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate

Reférences

Fiche technique

Anti-Human DNAJB6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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