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Anti-Human DNAJC2 Polyclonal Antibody (HV184014)

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Anti-Human DNAJC2 Polyclonal Antibody
Anti-Human DNAJC2 Polyclonal Antibody
Precio(USD): --
Especificación:
  • 50ug
  • 100ug
Número:
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Vista general
Número de catálogoHV184014
Descripción
Anti-Human DNAJC2 Polyclonal Antibody (HV184014) is a rabbit polyclonal antibody detecting DNAJC2. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human DNAJC2 (Lys442-Lys621).
Objetivo DNAJC2, DnaJ homolog subfamily C member 2, DnaJ homolog subfamily C member 2, N-terminally processed, M-phase phosphoprotein 11, MPHOSPH11, MPP11, ZRF1, Zuotin-related factor 1
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q99543
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

DnaJ homolog subfamily C member 2 (DNAJC2) is a ~71 kDa protein. Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.

Nota For research use only
Imágenes
  • Anti-Human DNAJC2 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-DNAJC2 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Caco2 cell lysate
    Lane 2: HT-29 cell lysate
    Lane 3: Hela cell lysate
    Lane 4: HepG2 cell lysate
    Lane 5: K562 cell lysate
    Lane 6: PC-3 cell lysate
    Lane 7: NIH3T3 cell lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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