Anti-Human DNMT1 IP Recombinant Antibody (SAA0251) (HB924013)

Name: Anti-Human DNMT1 IP Recombinant Antibody (SAA0251)
Brand: abinScience
SKU: HB924013
Price: 191 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB924013

Reactivité des espèces

Human

Applications

ELISA, IF, IP

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a

ID de clone

SAA0251

Cible

CXXC-type zinc finger protein 9, MCMT, AIM, DNMT1, DNA MTase HsaI, DNMT, DNA (cytosine-5)-methyltransferase 1, Dnmt1, DNA methyltransferase HsaI, M.HsaI, CXXC9

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P26358

RRID

Anti-Human DNMT1 IP Antibody (SAA0251) (abinScience Cat# HB924013, RRID:AB_3729785)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

DNA (cytosine-5)-methyltransferase 1 (DNMT1) is a ~183 kDa protein. DNA methyltransferase that methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development.

1. Schlesinger, Y. et al. (2007) Nature genetics 39, 232-6. PMID: 17200670

2. Pradhan, M. et al. (2008) Biochemistry 47, 10000-9. PMID: 18754681

3. Felle, M. et al. (2011) Nucleic acids research 39, 8355-65. PMID: 21745816

4. Zhang, ZM. et al. (2015) Journal of molecular biology 427, 2520-2531. PMID: 26070743

5. Viré, E. et al. (2006) Nature 439, 871-4. PMID: 16357870

8. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human DNMT1 IP Antibody (SAA0251)

Reférences

Fiche technique

Anti-Human DNMT1 IP Recombinant Antibody (SAA0251).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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