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| カタログ番号 | HP484013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human DOT1L IP Recombinant Antibody (SAA0200) (HP484013) is a mouse monoclonal antibody detecting DOT1L in ELISA, IF, IP, IP-MS. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP, IP-MS | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA0200 | ||||
| ターゲット | DOT1-like protein, Lysine N-methyltransferase 4, DOT1L, Histone-lysine N-methyltransferase, H3 lysine-79 specific, KMT4, H3-K79-HMTase, KIAA1814, Histone H3-K79 methyltransferase | ||||
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q8TEK3 | ||||
| RRID | Anti-Human DOT1L IP Antibody (SAA0200) (abinScience Cat# HP484013, RRID:AB_3729734) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Histone-lysine N-methyltransferase, H3 lysine-79 specific (DOT1L) is a ~164 kDa protein. Histone methyltransferase that methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. 1. Feng, Q. et al. (2002) Current biology : CB 12, 1052-8. PMID: 12123582 2. Frisbie, VS. et al. (2024) Nature communications 15, 2467. PMID: 38503750 3. Singh, PR. et al. (2023) Nature communications 14, 8497. PMID: 38129415 4. Min, J. et al. (2003) Cell 112, 711-23. PMID: 12628190 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507) |
SDS-PAGE for Anti-Human DOT1L IP Antibody (SAA0200)
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