Anti-Human DSC2 Recombinant Antibody (SAA1658) (HX236013)

Name: Anti-Human DSC2 Recombinant Antibody (SAA1658)
Brand: abinScience
SKU: HX236013
Price: 196 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX236013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1658

Cible

Desmosomal glycoprotein II, Desmocollin-2, DSC2, DSC3, Cadherin family member 2, CDHF2, Desmosomal glycoprotein III, Desmocollin-3

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q02487

RRID

Anti-Human DSC2 Antibody (SAA1658) (abinScience Cat# HX236013, RRID:AB_3727419)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Desmocollin-2 (DSC2) is a ~99 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Promotes timely incorporation of DSG2 into desmosome intercellular junctions and promotes interaction of desmosome cell junctions with intermediate filament cytokeratin, via modulation of DSP phosphorylation. Plays an important role in desmosome-mediated maintenance of intestinal epithelial cell intercellular adhesion strength and barrier function. Positively regulates wound healing of intestinal mucosa via promotion of epithelial cell migration, and also plays a role in mechanotransduction of force between intestinal epithelial cells and extracellular matrix. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

1. Raya-Sandino, A. et al. (2021) Molecular biology of the cell 32, 753-768. PMID: 33596089

2. Flemming, S. et al. (2020) Molecular biology of the cell 31, 407-418. PMID: 31967937

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human DSC2 Antibody (SAA1658)

Reférences

Fiche technique

Anti-Human DSC2 Recombinant Antibody (SAA1658).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai